不知道多久以前在朋友圈看到转发分享：因为疫情，Johns Hopkins的Project Muse 限时免费，包括普林斯顿、康奈尔、乔治亚、哈佛、港中文、ACA、Early Theatre等40多家出版社基本都开放了自己的电子资料库，共有近24000本原版英文书，282本期刊。 链接是：https://about.muse.jhu.edu/resources/freeresourcescovid19/

我就随便点开看了看，顺手把它们转存了，但直到今天还没有打开任意一本书，的确，收藏就是雪藏！

我们真心不缺资源，缺的是时间以及学习氛围，如果你也认同这一点，也确实感觉自学困难，不妨考虑跟着我们生信技能树的教学团队一起学习，或者分享给你身边的博士后以及年轻生物学PI，帮助他们多一点数据认知，让科研更上一个台阶：

• 生信爆款入门-全球听（买一得五）（第4期），你的生物信息学入门课
• 数据挖掘第2期（两天变三周，实力加量），医学生/临床医师首选技能提高课

简单看了看目录，分享其中3个吸引我眼球的哈。

Genetics and Genomics of Eye Disease

副标题 Advancing to Precision Medicine， Book • 2019

虽然说研究的对象是眼部疾病，但是整体来说偏重于生物信息学（Genetics and Genomics ）

链接是：https://www.sciencedirect.com/book/9780128162224/genetics-and-genomics-of-eye-disease

章节目录如下：

Part I: Introduction to gene mapping

• Chapter 1 - Timeline of key discoveries in ophthalmic genetics
• Chapter 2 - Segregation, linkage, GWAS, and sequencing
  

  Part II: Genomics in the eye

• Chapter 3 - Whole-exome sequencing and whole-genome sequencing
• Chapter 4 - RNA sequencing and transcriptome analysis
• Chapter 5 - Noncoding genome in eye disease
  

  Part III: Mendelian disorders and high penetrant mutations

• Chapter 6 - Genetic architecture of inherited retinal disease
• Chapter 7 - Early-onset glaucoma
  Carly J. van der Heide, Matthew A. Miller and John H. Fingert
• Chapter 8 - Bardet-Biedl syndrome
• Chapter 9 - Hereditary predisposition to uveal melanoma
  

  Part IV: Complex disorders and low effect-size risk factors

• Chapter 10 - Age-related macular degeneration
• Chapter 11 - Genetics of primary open-angle glaucoma
• Chapter 12 - Genetics of diabetic retinopathy
• Chapter 13 - Genetics of keratoconus
  

  Part V: Genetic testing and genetic risk prediction

• Chapter 14 - Genetic testing of various eye disorders
• Chapter 15 - Genetic risk scores in complex eye disorders
  

  Part VI: Gene-based therapy

• Chapter 16 - Gene therapy for inherited retinal diseases
• Chapter 17 - Gene therapy in animal models

Part VII: Big data and precision medicine

Data Processing Handbook for Complex Biological Data Sources

纯粹的生物信息学啦。

链接是：https://www.sciencedirect.com/book/9780128165485/data-processing-handbook-for-complex-biological-data-sources

章节目录如下：

• Chapter 1 - Mass spectroscopy
• Chapter 2 - Circular dichroism
• Chapter 3 - Fluorescence spectroscopy
• Chapter 4 - High-throughput sequencing
• Chapter 5 - Nuclear magnetic resonance
• Chapter 6 - Fourier transform infrared spectroscopy: Data interpretation and applications in structure elucidation and analysis of small molecules and nanostructures
• Chapter 7 - Microscopy
• Chapter 8 - Principles and applications of flow cytometry
• Chapter 9 - Isothermal titration calorimetry
• Chapter 10 - Metagenome analysis and interpretation

似乎只有第4章的高通量测序数据才勉强算是生物信息学里面的。

Encyclopedia of Bioinformatics and Computational Biology

Reference Work • 2019

链接是：https://www.sciencedirect.com/referencework/9780128114322/encyclopedia-of-bioinformatics-and-computational-biology

这本书内容多达三千多页，值得专门推荐！