然后基于此，把TCGA计划里面的所有癌症样本数据都处理了，并且得到了融合基因数据集，然后就以此出售
Pricing of FusionSCOUT datasets:
- Single gene in one cancer set 490€ / 580$ per dataset
- Single gene fusions across all cancers 4900€ / 5800$ dataset
- Individual cancer set 990 € / 1250 $ per dataset
- Full TCGA dataset 9900€ / 12500$ per dataset
One of the latest therapeutics angles in the fight against cancer is fusion genes and their regulation. To aid in fusion gene research and reveal the multitude of gene fusion event in cancer samples MediSapiens has developed a proprietary FusionSCOUT pipeline for identifying fusion genes from RNA sequencing datasets.
Currently we have analysed 7625 tumour samples from the TCGA project building a fusion gene dataset covering 28 different cancers within the TCGA project which can be accessed through our FusionSCOUT product.
Using this pipeline, we have discovered 3930 samples with gene fusions with 9667 different fusion genes. We´ve discovered numerous novel gene fusions as well as new cancer types in which previously known fusions appear.
You can now purchase these gene fusions datasets with few mouse clicks and get the worlds most comprehensive gene fusions from cancer sets within days
FusionSCOUT cancer Reports
With FusionSCOUT you can access the full listings of all fusion genes in specific cancer datasets. Find new leads for possible cause of the cancer, examine the pathways that are affected by different fusions, stratify patients by shared fusion genes or search for potential target for drugs and companion diagnostics.
Once you purchase a FusionSCOUT dataset we will send you a detailed report with information on the fused genes, sample ID from the TCGA dataset, fusion frequencies across the dataset as well as fusion mRNA sequences and lists of protein domains present in the fusion transcripts.
By ordering the MediSapiens FusionSCOUT dataset, you´ll get:
- A list of all gene fusions that involve your gene of interest, across all TCGA cancer types
- TCGA sample ID: s of the for the samples with fusions
- Exact exon junctions for the fusions, including alternatively spliced variants and data on whether reading frame is retained
- Detailed list of protein domains retained in the fusion genes
- cDNA sequence for the fusion mRNAs
Contact us to access the most up-to-date and comprehensive datasets of fusion gene events in different cancers!contact@medisapiens.com
Check out also our Fusion Gene Detection pipeline service for your samples!
Dataset missing? Email us and well add your favorite dataset to FusionSCOUT!
FusionSCOUT Cancer sets, March 2015
| Cancer type | Number of samples | Number of fusion genes |
| Acute Myeloid Leukemia, LAML | 153 | 69 |
| Adrenocortical carcinoma, ACC | 79 | 115 |
| Bladder Urothelial Carcinoma, BLCA | 273 | 473 |
| Brain Lower Grade Glioma, LGG | 467 | 309 |
| Breast Invasive Carcinoma, BRCA | 1029 | 3267 |
| Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma, CESC | 195 | 190 |
| Colon Adenocarcinoma, COAD | 287 | 212 |
| Glioblastoma multiforme, GBM | 170 | 379 |
| Head and Neck Squamous Cell Carcinoma, HNSC | 412 | 386 |
| Kidney Chromophobe, KICH | 66 | 19 |
| Kidney Renal Clear Cell Carcinoma, KIRC | 523 | 217 |
| Kidney Renal Papillary Cell Carcinoma, KIRP | 226 | 145 |
| Liver Hepatocellular Carcinoma, LIHC | 198 | 317 |
| Lung Adenocarcinoma, LUAD | 456 | 991 |
| Lung Squamous Cell Carcinoma, LUSC | 482 | 1374 |
| Lymphoid Neoplasm Diffuse Large B-cell Lymphoma, DLBC | 28 | 18 |
| Mesothelioma, MESO | 36 | 26 |
| Ovarian Serous Cystadenocarcinoma, OV | 420 | 1166 |
| Pancreatic Adenocarcinoma, PAAD | 84 | 46 |
| Pheochromocytoma and Paraganglioma, PCPG | 184 | 83 |
| Prostate Adenocarcinoma, PRAD | 336 | 859 |
| Rectum Adenocarcinoma, READ | 85 | 74 |
| Sarcoma, SARC | 161 | 799 |
| Skin Cutaneous Melanoma, SKCM | 355 | 620 |
| Stomach Adenocarcinoma, STAD | 190 | 311 |
| Thyroid Carcinoma, THCA | 506 | 195 |
| Uterine Carcinosarcoma, UCS | 57 | 229 |
| Uterine Corpus Endometrial Carcinoma, UCEC | 167 | 422 |