其实国际三大主流生物信息学数据库运营单位都出了自己的基因组坐标转换,它们分别是 (UCSC liftOver, NCBI Remap, Ensembl API)
Ensembl's Assembly Converter.是基于crossmap的,我觉得挺好用的,就介绍给大家!!!
This online tool currently uses CrossMap, which supports a limited number of formats (see our online documentation for details of the individual data formats listed below). CrossMap also discards metadata in files, so track definitions, etc, will be lost on conversion.
Important note: CrossMap converts WIG files to BedGraph internally for efficiency, and also outputs them in BedGraph format.
但是不知道为什么UCSC的liftover最出名,我也写过它的教程,(http://www.bio-info-trainee.com/?p=990)